Observer Effect and Ecology

In at least one case, generally accepted, the Observer Effect is literal--since visibility involves the loss of an electron, an object is altered simply by being observed.  But, more slowly coming into acceptance is the recognition that the cause of variability is the general condition that can be called the Experimenter Effect.  Guiding this analysis is the Ecological principle that everything is in interaction with its environment, a principle from which experimentation has long been presumed to be exempt, because of the efforts taken to isolate the context from its surroundings.  But, perfect isolation is similar to concepts such as a frictionless surface--a heuristic device, rather than an actuality, the imperfections of which become detectable by unprecedentedly precise instruments at the Quantum level.  So, the objections to the Observer Effect need to accommodate the Ecological defense of it.